Onglyza Lawsuit

Popular Diabetes drug Onglyza (saxagliptin) may be linked to a number of serious side effets including, bullous pemphigoid, heart failure, heart attack, and stroke. Some of those who have been diagnosed with these life threatening conditions, after taking Onglyza, have contacted law firms like ours to discuss their rights with regard to pursuing a lawsuit against the manufacturer.

2.5 and 5 mg Onglyza tablets in bottles

2.5 and 5 mg Onglyza tablets in bottles

Onglyza (sazagliptin) belongs to a new group of drugs, called DPP-4 inhibitors, used to treat Type 2 Diabetes. It was approved in 2009. Since then Onglyza has been associated with numerous life threatening side effects. This has lead a number of patients diagnosed with heart failure, heart attack, or stroke while taking Onglyza to seek the assistance of a product liability firm like ours.

What Is Onglyza?

Onglyza (sazagliptin) is a drug used to treat Type 2 Diabetes. It was approved by The FDA in 2009 and was introduced to the American marketplace soon after. It belongs to a “next generation” group of diabetes meds called DPP-4 inhibitors. These drugs work by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This stimulates the activity of incretins, which play an important role in insulin secretion and blood glucose control regulation.

Side Effects Of Onglyza

More than 100 million Americans have diabetes or prediabetes. This massive base of consumers have given drug companies like AstraZeneca reason to invest large sums of money in research and development into new medications used to treat Type 2 Diabetes. The most recent “breakthrough” in treating Type 2 Diabetes has been DPP-4 inhibitors. This type of drug was first characterized the late 90’s and rose to prevalence in the late 00’s with the FDA’s approval of Januvia (Sitagliptin), Galvus (Vildagliptin), Onglyza (Saxagliptin), and Tradjenta (Linagliptin). All of these DPP-4 inhibitor drugs have faced scrutiny after reports to the FDA Adverse Event Reporting System (FAERS).

Major side effects that may be associated with Onglyza include:

  • Bullous Pemphigoid – A painful autoimmune condition that causes large blisters between the inner layers of the skin. It is almost always described as “extremely painful.”
  • Heart Attack – A sudden and sometimes fatal occurrence of coronary thrombosis, typically resulting in the death of part of a heart muscle.
  • Heart Failure – A chronic disease that causes the heart to not be able to pump blood as it usually would. Heart Failure is often fatal.
  • Stroke – Damage to the brain from interruption of its blood supply.

If you or a loved one has experienced any of these conditions while on, or after taking, Onglyza you are not alone.

Injured by Side Effects of Onglyza?
If you or a loved one has suffered side effects after taking Onglyza, you are not alone. To learn how we can help you and your family, please contact us for a Free Case Evaluation. We would be honored to speak with you and will respond promptly to every inquiry we receive.
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Onglyza And Bullous Pemphigoid

Certain DPP-4 inhibitor class drugs, including Onglyza, may be linked to the debilitating autoimmune disease bullous pemphigoid. This disease is usually characterized by large, fluid filled blisters that are hard to rupture. They form under the first and second layers of skin and usually cluster in the pits and folds of the body, such as the armpits, groin, elbows, knee pits and across the torso. It is thought that Onglyza’s over stimulation of the pancreas may contribute to bullous pemphigoid. Based, in part, on these reports, the manufacturer of Onglyza amended the label in January, 2017 to warn of the risk of bullous pemphigoid.

Onglyza And Heart Failure

Contrary to popular thought, Heart Failure is a long term disease and not a single event of the heart stopping. Heart Failure causes a weakened heart, which prevents the organ from properly circulating blood through the body. Left undiagnosed or untreated, Heart Failure is almost always fatal. Reports have surfaced associating the use of drugs like Onglyza to the life threatening disease. You should contact your doctor immediately if they develop any of the following signs or symptoms:

  • Unusual shortness of breath during daily activities
  • Trouble breathing when lying down
  • Tiredness, weakness, or fatigue
  • Weight gain with swelling in the ankles, feet, legs, or stomach

Onglyza And Heart Attack

DPP-4 inhibitor drugs including Onglyza may also cause heart problems that could result in a heart attack. Some consumer watchdog groups have called for tougher regulation on DPP-4 inhibitor drugs.

Onglyza And Stroke

It has also been reported that Onglyza may cause stoke complications.  If you or a loved one has experienced any of the following symptoms while taking Onglyza, contact your doctor immediately:

  • F: Face drooping. Ask the person to smile, and see if one side is drooping. One side of the face may also be numb, and the smile may appear uneven.
  • A: Arm weakness. Ask the person to raise both arms. Is there weakness or numbness on one side? One arm drifting downward is a sign of one-sided arm weakness.
  • S: Speech difficulty. People having a stroke may slur their speech or have trouble speaking at all. Speech may be incomprehensible. Ask the person to repeat a simple sentence and look for any speech abnormality.
  • T: Time to call 9-1-1! If a person shows any of the symptoms above, even if the symptoms went away, call 9-1-1 and get the person to a hospital immediately.

This self monitoring technique is known as the FAST system. While it is by no means a comprehensive symptoms list, it may help save your life through quick action.

Onglyza Lawsuit In Review

Popular Diabetes drug Onglyza (saxagliptin) may be linked to a number of side effects including, bullous pemphigoid, heart failure, heart attack, and stroke. Those affected by these debilitating side effects, while taking Onglyza, are urged to speak with a law firm to discuss their legal rights in pursuing a lawsuit against the manufacturer.

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